Outcomes of Rescue PCI Following Failed Thrombolysis: Clinical Efficacy, Predictors, and Long-Term Prognosis

doi:N/A

Bangaldesh Journal of Cardivascular Medicine

2024, Volume 2, Issue 3 : 1-6

Research Article

Outcomes of Rescue PCI Following Failed Thrombolysis: Clinical Efficacy, Predictors, and Long-Term Prognosis

James R. Mitchell

Sarah K. Ahmed

David L. Thompson

Department of Cardiology, Global Heart Research Institute, Boston, USA

Department of Interventional Cardiology, International Cardiovascular Research Centre, London, UK

Department of Cardiovascular Medicine, European Institute of Heart Sciences, Berlin, Germany

Abstract

Rescue percutaneous coronary intervention (Rescue PCI) is an important reperfusion strategy for patients with ST-segment elevation myocardial infarction (STEMI) who fail to achieve adequate reperfusion following thrombolytic therapy. Although primary PCI remains the preferred reperfusion modality, thrombolysis continues to be widely used in regions where timely PCI is unavailable. Failed thrombolysis is associated with persistent coronary occlusion, ongoing myocardial ischemia, larger infarct size, heart failure, and increased mortality. Rescue PCI aims to restore coronary blood flow and limit myocardial damage in such patients. This study reviews the clinical outcomes, predictors, procedural considerations, complications, and long-term prognosis of Rescue PCI following failed thrombolysis. A comprehensive framework for patient selection and management is proposed based on current evidence and guideline recommendations.

Keywords

Rescue PCI

Failed Thrombolysis

STEMI

Myocardial Infarction

Coronary Intervention

Reperfusion Therapy

Cardiovascular Outcomes

Interventional Cardiology

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