Contemporary Outcomes of Primary PCI in STEMI Patients in South Asia: A Multicenter Observational Study

doi:N/A

Bangaldesh Journal of Cardivascular Medicine

2024, Volume 2, Issue 1 : 1-6

Research Article

Contemporary Outcomes of Primary PCI in STEMI Patients in South Asia: A Multicenter Observational Study

Ahsan M. Rahman

Priya K. Sharma

Mohammad Faisal Hossain

Ravi Perera

⁴

Department of Cardiology, South Asian Institute of Cardiovascular Sciences, Dhaka, Bangladesh

Department of Interventional Cardiology, National Heart Research Centre, New Delhi, India

Department of Cardiovascular Medicine, Chittagong Medical Research Institute, Chattogram, Bangladesh

⁴

Department of Cardiology, Colombo Heart and Vascular Centre, Colombo, Sri Lanka

Abstract

Background

Primary Percutaneous Coronary Intervention (PPCI) remains the gold-standard reperfusion strategy for ST-Elevation Myocardial Infarction (STEMI). Despite substantial advancements in interventional cardiology, disparities in healthcare infrastructure, patient demographics, and treatment accessibility continue to influence outcomes across South Asia.

Objective

To evaluate contemporary clinical outcomes of primary PCI among STEMI patients in South Asia and identify predictors of adverse cardiovascular events.

Methods

A multicenter observational study involving 1,250 STEMI patients undergoing primary PCI across Bangladesh, India, Sri Lanka, Nepal, and Pakistan between January 2022 and December 2024 was conducted. Demographic, procedural, and clinical outcome data were analyzed.

Results

The mean age was 57.8 ± 11.6 years. Males represented 78.4% of participants. Successful reperfusion (TIMI III flow) was achieved in 92.8% of patients. In-hospital mortality was 4.6%, while 30-day mortality was 6.2%. Major adverse cardiovascular events (MACE) occurred in 10.4% of patients. Door-to-balloon time below 90 minutes significantly reduced mortality (p < 0.001).

Conclusion

Primary PCI demonstrates excellent contemporary outcomes in South Asia despite regional healthcare challenges. Early presentation, reduced door-to-balloon time, radial access, and complete revascularization significantly improve patient outcomes.

Keywords

STEMI

Primary PCI

South Asia

Coronary Intervention

Acute Myocardial Infarction

MACE

Reperfusion Therapy

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