Clinical Outcomes of Transcatheter Aortic Valve Implantation in Elderly Patients: Procedural Success, Safety, and Short-Term Mortality

doi:N/A

Bangaldesh Journal of Cardivascular Medicine

2024, Volume 2, Issue 4 : 1-7

Research Article

Clinical Outcomes of Transcatheter Aortic Valve Implantation in Elderly Patients: Procedural Success, Safety, and Short-Term Mortality

Mohammad A. Rahman

Priya K. Sharma

Ravi Perera

Ahmed S. Hossain

⁴

Department of Interventional Cardiology, Bangladesh Institute of Cardiovascular Sciences, Dhaka, Bangladesh

Department of Structural Heart Disease, National Heart Research Centre, New Delhi, India

Department of Cardiology, Colombo Heart and Vascular Institute, Colombo, Sri Lanka

⁴

Department of Cardiovascular Medicine, South Asian Medical Research Centre, Chattogram, Bangladesh

Abstract

Background

Transcatheter Aortic Valve Implantation (TAVI) has emerged as an effective alternative to surgical aortic valve replacement in elderly patients with severe symptomatic aortic stenosis, especially those at high surgical risk.

Objective

To evaluate procedural success, safety outcomes, mortality, and functional improvement following TAVI in elderly patients.

Methods

A prospective multicenter observational study was conducted among 685 elderly patients aged ≥75 years undergoing TAVI between January 2021 and December 2024 across tertiary cardiac centers in South Asia. Clinical, echocardiographic, procedural, and 30-day outcome data were analyzed.

Results

Mean age was 81.6 ± 5.4 years. Procedural success was achieved in 96.2% of cases. Thirty-day mortality was 5.7%. Major vascular complications occurred in 6.4%, stroke in 2.6%, and permanent pacemaker implantation in 11.8%. Significant improvement was observed in mean aortic valve gradient and NYHA functional class after TAVI.

Conclusion

TAVI is a safe and effective treatment option for elderly patients with severe symptomatic aortic stenosis. The procedure provides high success rates, acceptable short-term mortality, improved hemodynamic performance, and significant functional recovery.

Keywords

TAVI

TAVR

Aortic Stenosis

Elderly Patients

Structural Heart Intervention

Mortality

Functional Outcomes

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